Endocrine Abstracts

Excitatory amino acid neurotransmitters (EAA) play an essential role in regulation of GH secretion in the central nervous system. Involvement of EAA path way in the secretion of GH was indicated by early finding that NMA stimulate GH secretion via direct release of hypothalamic GHRH. The present study was designed to investigate the involvement of excitatory amino acid neurotransmitter’s (EAA) pathway in the regulation of basal as well as stimulated GH secretion in primat...

Hypoglycemia result in significant activation of various neuroendocrine pathways involved in producing peripheral hormonal and metabolic responses aimed at restoring euglycemia. The present study was designed to investigate the involvement of excitatory amino acid neurotransmitter’s (EAA) pathway in the regulation of basal as well as physiologically stimulated PRL secretion in primates. Four adult male Rhesus monkeys (Macaca mulata) were used in the study. Four set...

The endogenous opiates cause a rapid increase in PRL secretion. The present study was designed to investigate the involvement of opioidergic pathway in the regulation of PRL secretion by the endogenous excitatory neurotransmitters in primates. In the first set of experiments saline infusion (3 ml/h) for a period of 3 h was given. In the second set of experiment NMA injections were administered with one hr interval. In the third set of experiment NAL infusion (5 mg/3 ml per h) ...